CYANOACETIC ACID
Pharmaceutical Intermediate

1. STRUCTURE
Cyanoacetic Acid
2. PRODUCT NAME & DETAILS
Product Name Cyanoacetic Acid
Product Code 003516
CAS No 372-09-8
HS Code 2926.90.00
Molecular Formula C3H3NO2
Molecular Wt. 85.06
Synonyms 2-cyanoacetic acid
3. SPECIFICATION
Freezing Point
64-68°C
Physical Appearance
A White To Slightly Yellowish Crystalline Hygroscopic Cr
Water Content (KF)
NMT 1.0%
Solubility
Clear Solution (5% In Water Is Clear)
Assay By Titration
NLT 98%
Purity By HPLC
NLT 97%
4. APPLICATION - It is used as raw material to manufacture industrial organic chemicals.

- Cyanoacetic acid was used in the synthesis of N-piperidine-cyanacetamide and N-morpholyl-cyanacetamide.
It was also used in the preparation of a panchromatic dye for dye-sensitized solar cells.

- Cyanoacetic acid can be used as a reagent:
• Along with acetic anhydride for cyanoacetylation of various pyrroles, indoles, and aniline derivatives.
It can also be used in other reactions such as cyclizations, syntheses of coumarins and other heterocycles.
• To prepare of key intermediate via Knoevenagel condensation in the total synthesis of 5-acetamido-substituted
melatonin derivatives as MT3 receptor ligands.
• In the synthesis of aminopyrrolinone derivatives by reacting Ugi adducts of cyanoacetic acid and aromatic aldehydes.

- The largest scale reaction is its esterification to give the corresponding ester ethyl cyanoacetate, which is then
transformed to ethyl cyanoacrylate used as superglue, via reaction with formaldehyde.

- It is a precursor to synthetic caffeine via the intermediacy of theophylline. It is a building block for many drugs,
including dextromethorphan, amiloride, sulfadimethoxine, and allopurinol, and also for Peldesine.
5. HAZARD CLASSIFICATION
Hazardous substance. (UN No. 3261)

Irritant

Corrosive

6. CAPACITY 5 MT per year.
7. STORAGE CONDITION
Store in closed container at ambient temperature. Avoid direct sun light.
8. PACKING DETAILS
20 kg net in HDPE container with two PE liners, strip sealed separately.
9. SHELF LIFE
6 months.
Disclaimer
Typical properties should not be considered as specification.
Product covered by valid patents are not offered or supplied for commercial use. The Patent position should be verified by the customer.
Products will not be supplied to countries where they could be in conflict with existing patents.
Products currently covered by valid US patents are offered for R&D use in accordance with 35 USC 271 (e) (I) Above information is given in good faith and without warrenty.

The above information is given in good faith and is without warranty

Frequently Asked Questions

What Are the Application & Uses of Cyanoacetic acid?

Cyanoacetic acid is an organic compound and a widely used pharmaceutical intermediate. Cyanoacetic acid is also used as a raw material to manufacture industrial organic chemicals.

What Is a Unique Numerical Identifier (Cas No) Assigned to Cyanoacetic acid?

The given unique CAS registry number for Cyanoacetic acid is “372-09-8”. This CAS NO is global identification for this chemical anyone wanted to get Cyanoacetic acid for production/research purpose can find it with the help of this number.

What Are Some of the Major Specifications of Cyanoacetic acid?

Cyanoacetic acid is an "A White To Slightly Yellowish Crystalline Hygroscopic Cr" and has a freezing point of 64-68°C. The Molecular Formula of Cyanoacetic acid is "C3H3NO2" and the Molecular Wt. is 85.06.

What Size of Chemicals Packing for Cyanoacetic acid does Sarex Offers?

Sarex Offers 20 kg net of Cyanoacetic acid in HDPE container with two PE liners, strip sealed separately. Contact Us For More Information!

What Are the Hazardous Classifications of Cyanoacetic acid?

Cyanoacetic acid is a Hazardous substance (Corrosive, Irritant) substance. (UN No. 3261)

What Is the Annual Capacity of Cyanoacetic acid?

The annual capacity of Cyanoacetic acid is 5 MT per year.

What Is the Perfect Storage Condition & Shelf Life for Cyanoacetic acid?

The Perfect Storage condition for Cyanoacetic acid is that Store in a closed container at ambient temperature. Avoid direct sunlight and has a shelf life of 6 months.

Cas No: 372-09-8 | Molecular Formula: C3H3NO2