| 1. STRUCTURE | |
|---|---|
 |
| 2. PRODUCT NAME & DETAILS | |
|---|---|
| Product Name | 6-Nitro-7-chloro-4-hydroxy quinazoline |
| Product Code | 002694 |
| CAS No | 53449-14-2 |
| HS Code | 2933.99.00 |
| Molecular Formula | C8H4CIN3O3 |
| Molecular Wt. | 225.590 |
| Synonyms | 7-Chloro-6-nitro-4(3H)quinazolinone, 7-Chloro-4-hydroxy-6-nitroquinazoline, 7-chloro-6-nitro-3H-quinazolin-4-one |
| 3. Regulatory Information
|
|||
| Chemical name
|
Common names and synonyms
|
CAS number
|
EC number
|
| 6-Nitro-7-chloro-4-hydroxy quinazoline
|
7-Chloro-6-nitroquinazoline-4-ol
|
53449-14-2
|
678-360-9
|
| European Inventory of Existing Commercial Chemical Substances (EINECS)
|
Not Listed
|
||
| EC Inventory | Not Listed
|
||
| United States Toxic Substances Control Act (TSCA) Inventory
|
Not Listed
|
||
| China Catalog of Hazardous chemicals 2015
|
Not Listed
|
||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)
|
Not Listed
|
||
| Korea Existing Chemicals List (KECL)
|
Not Listed
|
||
| Canadian Domestic Substance List (DSL)
|
Not Listed
|
||
| Canadian Non-Domestic Substance List (NDSL)
|
Not Listed
|
||
| Japanese Existing and New Chemical Substances Inventory(ENCS)
|
Not Listed
|
||
| 4. SPECIFICATION
|
|
| Physical Appearance
|
Pale Yellow Powder to Light Brown Powder
|
| Melting Point
|
Min. 300.0 °C
|
| Identification (HPLC)
|
RT of Sample Should Matches with Standard
|
| Moisture Content (KF)
|
NMT 0.5%
|
| 7 Chloro-4[1h]-quinazolinone
|
MAX 0.5%
|
| Any Others Impurity 5,7-Dichloro-4[1h]quinazolinone
|
MAX 0.1%
|
| +7-chloro-8nitro-4[1h]quinazolin One
|
MAX 1.5%
|
| Assay (HPLC)
|
NLT 98%
|
| 5. APPLICATION | It is use as intermediate of Afatinib and Afatinib Dimaleate.
It is use in Anti-Cancer, Oncology Drug. |
||
| 6. HAZARD CLASSIFICATION | Hazardous Substance (UN No. 2811).
|
||
| 7. ANNUAL CAPACITY | 24 MT.
|
||
| 8. STORAGE CONDITION
|
Store in closed container at ambient temperature. Avoid direct sunlight.
|
||
| 9. PACKING DEATILS
|
Outer Packing : 25 kg HDPE UN Approved Open Mouth Drum
Inner Packing : 2 plastic liner with strip seal individually on each liner |
||
| 10. SHELF LIFE
|
1 year.
|
| Disclaimer |
|---|
| Typical properties should not be considered as specification. Product covered by valid patents are not offered or supplied for commercial use. The Patent position should be verified by the customer. Products will not be supplied to countries where they could be in conflict with existing patents. Products currently covered by valid US patents are offered for R&D use in accordance with 35 USC 271 (e) (I) Above information is given in good faith and without warrenty. |
The above information is given in good faith and is without warranty
Products Recommendations
2-(2-Hydroxy-4-methoxyphenyl)-4,6-Bis(phenyl)-1,3,5-triazine (Appolo-1579 (A-103))
CAS No. 106556-36-9
Automotive Coatings
2-(4-Methoxyphenyl)4,6-bis-(2,4-dihydroxyphenyl) -1,3,5-triazine (Appolo-125 (P))
CAS No. 1440-00-2
Sunscreen Lotion
2-Chloro-4,6-Bis(phenyl)-1,3,5-triazine (Stellar-2015)
CAS No. 3842-55-5
UV Absorber & Light Stablizer additive
2,4-Bis(2,4-dimethyl phenyl)-6-(2-hydroxy-4-methoxy phenyl)1,3,5-triazine (Appolo-1164 GL)
CAS No. 1820-28-6
UV Absorbers & Light Stabilizer additive
4-(2-Hydrazino-2-oxoethyl)-4-methylmorpholine-4-iumchloride (HMMC)
CAS No. 876-57-3
Pharmaceutical Intermediate
